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ZFN mediated genome editing

Showing 1 - 25 of 3,573
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Hemophilia B Trial in Washington (SB-FIX)

Terminated
  • Hemophilia B
  • SB-FIX
  • Washington, District of Columbia
    Georgetown University Medical Center
Mar 8, 2022

MPS I Trial in Oakland (SB-318)

Terminated
Has Results
  • MPS I
  • SB-318
  • Oakland, California
    UCSF Benioff Children's Hospital Oakland
Jan 6, 2023

Mucopolysaccharidosis II, MPS II Trial in United States (SB-913)

Terminated
Has Results
  • Mucopolysaccharidosis II
  • MPS II
  • SB-913
  • Oakland, California
  • +4 more
Oct 21, 2022

Transfusion Dependent Beta-thalassemia Trial in United States (ST-400 Investigational product)

Active, not recruiting
  • Transfusion Dependent Beta-thalassemia
  • ST-400 Investigational product
  • Los Angeles, California
  • +5 more
Jul 6, 2022

Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia, Non Hodgkin Lymphoma Trial (PACE CART19)

Withdrawn
  • Acute Lymphoblastic Leukemia
  • +2 more
  • PACE CART19
  • (no location specified)
Mar 9, 2022

(LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX

Active, not recruiting
  • Hemophilia B
  • +2 more
  • SB-318
  • +2 more
  • Oakland, California
  • +4 more
Jan 30, 2023

l Gene Editing Therapy for Cardiovascular Disease

Not yet recruiting
  • Atherosclerotic Cardiovascular Disease
  • +2 more
    • Auckland, New Zealand
    • +2 more
    Oct 31, 2023

    Neovascular Age-related Macular Degeneration(nAMD) Trial in Shanghai, Tianjin (HG202)

    Not yet recruiting
    • Neovascular Age-related Macular Degeneration(nAMD)
    • HG202
    • Shanghai, Shanghai, China
    • +1 more
    Sep 4, 2023

    Genetic Architecture of Neutrophil-Mediated Inflammatory Skin

    Not yet recruiting
    • Neutrophil-mediated Inflammatory Dermatoses
    • Inflammatory Dermatoses
    • Analysis of samples
    • Basel, Switzerland
      University Hospital Basel, Clinic of Dermatology
    Feb 20, 2023

    Congenital Hearing Loss Trial in Shanghai (HG205)

    Not yet recruiting
    • Congenital Hearing Loss
    • HG205
    • Shanghai, China
      Eye & ENT Hospital of Fudan University
    Aug 29, 2023

    ImplementingNational Biobank of PD With WGS and Functional

    Not yet recruiting
    • Parkinson Disease
    • REM Sleep Behavior Disorder
    • whole genome sequencing
    • Pozzilli, Italy
      IRCCS Neuromed
    Feb 13, 2023

    Gene Editing as a Therapeutic Approach for Rett Syndrome

    Recruiting
    • Rett Syndrome
    • Gene editing in vitro
    • Siena, Italy
      University of Siena
    Feb 13, 2023

    B Acute Lymphoblastic Leukemia Trial in London (PBLTT52CAR19)

    Recruiting
    • B Acute Lymphoblastic Leukemia
    • London, United Kingdom
      Great Ormond Street Hospital
    Dec 15, 2021

    Duchenne Muscular Dystrophy Trial in Worcester (CRD-TMH-001)

    Enrolling by invitation
    • Duchenne Muscular Dystrophy
    • Worcester, Massachusetts
      UMass Chan Medical School
    Aug 22, 2022

    NSCLC, Metastatic Non Small Cell Lung Cancer, Stage IV NSCLC Trial in Duarte, Minneapolis (Fludarabine, Cyclophosphamide, CISH

    Not yet recruiting
    • Carcinoma, Non-Small-Cell Lung
    • +5 more
    • Duarte, California
    • +1 more
    Dec 7, 2022

    Viral Keratitis, Blindness Eye, Herpes Simplex Virus Infection Trial in Shanghai (BD111 Adult single group Dose)

    Completed
    • Viral Keratitis
    • +3 more
    • BD111 Adult single group Dose
    • Shanghai, Shanghai, China
      Eye & Ent Hospital of Fudan University
    Aug 20, 2022

    Relapsed/Refractory Acute Myeloid Leukemia (AML) Trial in Dresden, Heidelberg (Donor-derived CD34+ HSC with CRISPR/Cas9-mediated

    Not yet recruiting
    • Relapsed/Refractory Acute Myeloid Leukemia (AML)
    • Donor-derived CD34+ HSC with CRISPR/Cas9-mediated CD33 deletion
    • Gemtuzumab Ozogamicin
    • Dresden, Germany
    • +1 more
    Dec 20, 2022

    Phenylketonurias, PAH Deficiency, Phenylketonuria Trial in United States (HMI-103)

    Recruiting
    • Phenylketonurias
    • +2 more
    • Orange, California
    • +5 more
    Oct 26, 2022

    Intraoperative Blood Pressure Changes and Whole Exome Genome

    Not yet recruiting
    • the Association Between the Arterial Stiffness, Intraoperative Blood Pressure Changes and Genetic Effect
    • this study did not involve interventions; it only observational study
    • (no location specified)
    Feb 7, 2023

    Disorder of Sex Development, 46,XY Trial in Montpellier (Identify structural variants by Optical Genome Mapping of DNA extracted

    Not yet recruiting
    • Disorder of Sex Development, 46,XY
    • Identify structural variants by Optical Genome Mapping of DNA extracted from blood leukocytes
    • Montpellier, France
      University Hospital Montpellier
    May 11, 2023

    Fertility Issues Trial in New York, Portland, Kirkland (Embryo genome sequencing, Parents genome sequencing)

    Not yet recruiting
    • Fertility Issues
    • Embryo genome sequencing
    • Parents genome sequencing
    • New York, New York
    • +2 more
    Feb 13, 2023

    Study of the Role of Genetic Modifiers in Hemoglobinopathies

    Recruiting
    • Sickle Cell Disease
    • +3 more
    • GWAS
    • Boston, Massachusetts
    • +24 more
    Apr 4, 2023

    Long Read Genome Sequencing in Patients Suffering From

    Recruiting
    • Genetic Disease
    • +3 more
      • Nantes, Loire-Atlantique, France
        Nantes University Hospital
      Jan 25, 2023

      Optical Genome Mapping in Characterization of Multiple Myeloma

      Not yet recruiting
      • Multiple Myeloma
      • Bone Marrow samples collection
      • Strasbourg, France
        Institut de cancérologie Strasbourg Europe
      Mar 15, 2023

      AML, Adult Trial (Biological characterization of AML with MECOM or atypical 3q26 rearrangements)

      Not yet recruiting
      • AML, Adult
      • Biological characterization of AML with MECOM or atypical 3q26 rearrangements
      • (no location specified)
      Apr 21, 2023